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Bacteria Induce Prolonged PMN Survival via a Phosphatidylcholine-Specific Phospholipase C- and Protein Kinase C-Dependent Mechanism

Polymorphonuclear leukocytes (PMNs) are essential for the human innate immune defense, limiting expansion of invading microorganisms. PMN turnover is controlled by apoptosis, but the regulating signaling pathways remain elusive, largely due to inherent differences between mice and humans that underm...

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Detalles Bibliográficos
Autores principales: Erttmann, Saskia F., Gekara, Nelson O., Fällman, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909253/
https://www.ncbi.nlm.nih.gov/pubmed/24498214
http://dx.doi.org/10.1371/journal.pone.0087859