A Novel Acylaminoimidazole Derivative, WN1316, Alleviates Disease Progression via Suppression of Glial Inflammation in ALS Mouse Model

Amyotrophic lateral sclerosis (ALS) is an adult-onset motor neuron degenerative disease. Given that oxidative stress and resulting chronic neuronal inflammation are thought to be central pathogenic, anti-oxidative agents and modulators of neuronal inflammation could be potential therapies for ALS. W...

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Detalles Bibliográficos
Autores principales: Tanaka, Kazunori, Kanno, Takuya, Yanagisawa, Yoshiko, Yasutake, Kaori, Inoue, Satoshi, Hirayama, Noriaki, Ikeda, Joh-E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909264/
https://www.ncbi.nlm.nih.gov/pubmed/24498180
http://dx.doi.org/10.1371/journal.pone.0087728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909264/
https://www.ncbi.nlm.nih.gov/pubmed/24498180
http://dx.doi.org/10.1371/journal.pone.0087728

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