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Co-Administration of Resveratrol and Lipoic Acid, or Their Synthetic Combination, Enhances Neuroprotection in a Rat Model of Ischemia/Reperfusion

The present study demonstrates the benefits of combinatorial antioxidant therapy in the treatment of ischemic stroke. Male Sprague-Dawley rats were anaesthetised and the middle cerebral artery (MCA) was occluded for 30 minutes followed by 5.5 hours of reperfusion. Pretreatment with resveratrol 30 mi...

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Detalles Bibliográficos
Autores principales: Saleh, Monique C., Connell, Barry J., Rajagopal, Desikan, Khan, Bobby V., Abd-El-Aziz, Alaa S., Kucukkaya, Inan, Saleh, Tarek M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909267/
https://www.ncbi.nlm.nih.gov/pubmed/24498217
http://dx.doi.org/10.1371/journal.pone.0087865