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Co-Administration of Resveratrol and Lipoic Acid, or Their Synthetic Combination, Enhances Neuroprotection in a Rat Model of Ischemia/Reperfusion
The present study demonstrates the benefits of combinatorial antioxidant therapy in the treatment of ischemic stroke. Male Sprague-Dawley rats were anaesthetised and the middle cerebral artery (MCA) was occluded for 30 minutes followed by 5.5 hours of reperfusion. Pretreatment with resveratrol 30 mi...
Autores principales: | Saleh, Monique C., Connell, Barry J., Rajagopal, Desikan, Khan, Bobby V., Abd-El-Aziz, Alaa S., Kucukkaya, Inan, Saleh, Tarek M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909267/ https://www.ncbi.nlm.nih.gov/pubmed/24498217 http://dx.doi.org/10.1371/journal.pone.0087865 |
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