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p53-Dependent and Cell Specific Epigenetic Regulation of the Polo-like kinases under Oxidative Stress
The polo-like kinase (PLKs) family, consisting of five known members, are key regulators of important cell cycle processes, which include mitotic entry, centrosome duplication, spindle assembly, and cytokinesis. The PLKs have been implicated in a variety of cancers, such as hepatocellular carcinoma...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909268/ https://www.ncbi.nlm.nih.gov/pubmed/24498222 http://dx.doi.org/10.1371/journal.pone.0087918 |