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p53-Dependent and Cell Specific Epigenetic Regulation of the Polo-like kinases under Oxidative Stress

The polo-like kinase (PLKs) family, consisting of five known members, are key regulators of important cell cycle processes, which include mitotic entry, centrosome duplication, spindle assembly, and cytokinesis. The PLKs have been implicated in a variety of cancers, such as hepatocellular carcinoma...

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Detalles Bibliográficos
Autores principales: Ward, Alejandra, Hudson, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909268/
https://www.ncbi.nlm.nih.gov/pubmed/24498222
http://dx.doi.org/10.1371/journal.pone.0087918