Accelerated Repair and Reduced Mutagenicity of DNA Damage Induced by Cigarette Smoke in Human Bronchial Cells Transfected with E.coli Formamidopyrimidine DNA Glycosylase

Cigarette smoke (CS) is associated to a number of pathologies including lung cancer. Its mutagenic and carcinogenic effects are partially linked to the presence of reactive oxygen species and polycyclic aromatic hydrocarbons (PAH) inducing DNA damage. The bacterial DNA repair enzyme formamidopyrimid...

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Detalles Bibliográficos
Autores principales: Foresta, Mara, Izzotti, Alberto, La Maestra, Sebastiano, Micale, Rosanna, Poggi, Alessandro, Vecchio, Donatella, Frosina, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909288/
https://www.ncbi.nlm.nih.gov/pubmed/24498234
http://dx.doi.org/10.1371/journal.pone.0087984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909288/
https://www.ncbi.nlm.nih.gov/pubmed/24498234
http://dx.doi.org/10.1371/journal.pone.0087984

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