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Modifier Genes as Therapeutics: The Nuclear Hormone Receptor Rev Erb Alpha (Nr1d1) Rescues Nr2e3 Associated Retinal Disease

Nuclear hormone receptors play a major role in many important biological processes. Most nuclear hormone receptors are ubiquitously expressed and regulate processes such as metabolism, circadian function, and development. They function in these processes to maintain homeostasis through modulation of...

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Detalles Bibliográficos
Autores principales: Cruz, Nelly M., Yuan, Yang, Leehy, Barrett D., Baid, Rinku, Kompella, Uday, DeAngelis, Margaret M., Escher, Pascal, Haider, Neena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909326/
https://www.ncbi.nlm.nih.gov/pubmed/24498227
http://dx.doi.org/10.1371/journal.pone.0087942