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Adenosine A(2B) receptors induce proliferation, invasion and activation of cAMP response element binding protein (CREB) in trophoblast cells
BACKGROUND: Placental hypoxia is a result of abnormal and shallow trophoblast invasion and involved in the pathophysiology of preeclampsia. Hypoxia increases extracellular adenosine levels and plays an important role in the regulation of angiogenesis, proliferation, vascular tone, endothelial permea...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909477/ https://www.ncbi.nlm.nih.gov/pubmed/24383849 http://dx.doi.org/10.1186/1471-2393-14-2 |