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Adenosine A(2B) receptors induce proliferation, invasion and activation of cAMP response element binding protein (CREB) in trophoblast cells

BACKGROUND: Placental hypoxia is a result of abnormal and shallow trophoblast invasion and involved in the pathophysiology of preeclampsia. Hypoxia increases extracellular adenosine levels and plays an important role in the regulation of angiogenesis, proliferation, vascular tone, endothelial permea...

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Detalles Bibliográficos
Autores principales: Darashchonak, Natallia, Koepsell, Brunhild, Bogdanova, Natalia, von Versen-Höynck, Frauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909477/
https://www.ncbi.nlm.nih.gov/pubmed/24383849
http://dx.doi.org/10.1186/1471-2393-14-2