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The multi-hit hypothesis in basal-like breast cancer

It has been known for many years that for a "normal" un-transformed cell to become immortal and subsequently tumorigenic requires multiple pro-oncogenic changes in the levels of protein expression and function. Genes most commonly associated with the process of oncogenesis include: p53 ina...

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Detalles Bibliográficos
Autor principal: Dent, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909545/
https://www.ncbi.nlm.nih.gov/pubmed/23974512
http://dx.doi.org/10.4161/cbt.26140