Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma

Granulocyte-macrophage colony-stimulating factor (GM-CSF) enhances immune responses by inducing dendritic cell proliferation, maturation, and migration and B and T lymphocyte expansion and differentiation. The potency of DNA vaccines can be enhanced by the addition of DNA encoding cytokines, acting...

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Detalles Bibliográficos
Autores principales: Perales, Miguel-Angel, Yuan, Jianda, Powel, Sarah, Gallardo, Humilidad F., Rasalan, Teresa S., Gonzalez, Christina, Manukian, Gregor, Wang, Jian, Zhang, Yan, Chapman, Paul B., Krown, Susan E., Livingston, Philip O., Ejadi, Samuel, Panageas, Katherine S., Engelhorn, Manuel E., Terzulli, Stephanie L., Houghton, Alan N., Wolchok, Jedd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909666/
https://www.ncbi.nlm.nih.gov/pubmed/18797450
http://dx.doi.org/10.1038/mt.2008.196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909666/
https://www.ncbi.nlm.nih.gov/pubmed/18797450
http://dx.doi.org/10.1038/mt.2008.196

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