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Absence of manganese superoxide dismutase delays p53-induced tumor formation()

BACKGROUND: Manganese superoxide dismutase (MnSOD) is a mitochondrial antioxidant enzyme that is down-regulated in a majority of cancers. Due to this observation, as well as MnSOD's potent antioxidant enzymatic activity, MnSOD has been suggested as a tumor suppressor for over 30 years. However,...

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Detalles Bibliográficos
Autores principales: Case, Adam J., Domann, Frederick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909777/
https://www.ncbi.nlm.nih.gov/pubmed/24494196
http://dx.doi.org/10.1016/j.redox.2014.01.001