A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice

The progressive bone marrow failure syndrome dyskeratosis congenita (DC) is often caused by mutations in telomerase or the factors involved in telomerase biogenesis and trafficking. However, a subset of DC patients is heterozygous for mutations in the shelterin component TIN2. To determine how the T...

Descripción completa

Detalles Bibliográficos
Autores principales: Frescas, David, de Lange, Titia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909789/
https://www.ncbi.nlm.nih.gov/pubmed/24449270
http://dx.doi.org/10.1101/gad.233395.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909789/
https://www.ncbi.nlm.nih.gov/pubmed/24449270
http://dx.doi.org/10.1101/gad.233395.113

Ejemplares similares