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Cellular senescence and its effector programs

Cellular senescence is a stress response that accompanies stable exit from the cell cycle. Classically, senescence, particularly in human cells, involves the p53 and p16/Rb pathways, and often both of these tumor suppressor pathways need to be abrogated to bypass senescence. In parallel, a number of...

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Detalles Bibliográficos
Autores principales: Salama, Rafik, Sadaie, Mahito, Hoare, Matthew, Narita, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909793/
https://www.ncbi.nlm.nih.gov/pubmed/24449267
http://dx.doi.org/10.1101/gad.235184.113