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Utility of network integrity methods in therapeutic target identification

Analysis of the biological gene networks involved in a disease may lead to the identification of therapeutic targets. Such analysis requires exploring network properties, in particular the importance of individual network nodes (i.e., genes). There are many measures that consider the importance of n...

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Detalles Bibliográficos
Autores principales: Peng, Qian, Schork, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909879/
https://www.ncbi.nlm.nih.gov/pubmed/24550933
http://dx.doi.org/10.3389/fgene.2014.00012