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Integrating influenza antigenic dynamics with molecular evolution

Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between influenza strains using the hemagglutination inhibition (HI) assay...

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Detalles Bibliográficos
Autores principales: Bedford, Trevor, Suchard, Marc A, Lemey, Philippe, Dudas, Gytis, Gregory, Victoria, Hay, Alan J, McCauley, John W, Russell, Colin A, Smith, Derek J, Rambaut, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909918/
https://www.ncbi.nlm.nih.gov/pubmed/24497547
http://dx.doi.org/10.7554/eLife.01914