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Use of a Population Pharmacokinetic Approach for the Clinical Development of a Fixed-Dose Subcutaneous Formulation of Trastuzumab

A new subcutaneous (s.c.) trastuzumab formulation provides savings in terms of time and is preferred by patients and health care professionals relative to standard intravenous (i.v.) administration due to simpler and more rapid administration (2–5 minutes). Selection of the s.c. dose was based on a...

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Detalles Bibliográficos
Autores principales: Hourcade-Potelleret, F, Lemenuel-Diot, A, McIntyre, C, Brewster, M, Lum, B, Bittner, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910009/
https://www.ncbi.nlm.nih.gov/pubmed/25019376
http://dx.doi.org/10.1038/psp.2013.63