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Scale Reduction of a Systems Coagulation Model With an Application to Modeling Pharmacokinetic–Pharmacodynamic Data

Bridging systems biology and pharmacokinetics–pharmacodynamics has resulted in models that are highly complex and complicated. They usually contain large numbers of states and parameters and describe multiple input–output relationships. Based on any given data set relating to a specific input–output...

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Detalles Bibliográficos
Autores principales: Gulati, A, Isbister, G K, Duffull, S B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910010/
https://www.ncbi.nlm.nih.gov/pubmed/24402117
http://dx.doi.org/10.1038/psp.2013.67