Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere

To protect against aneuploidy, chromosomes must attach to microtubules from opposite poles (‘biorientation’) prior to their segregation during mitosis. Biorientation relies on the correction of erroneous attachments by the aurora B kinase, which destabilizes kinetochore-microtubule attachments that...

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Detalles Bibliográficos
Autores principales: Verzijlbergen, Kitty F, Nerusheva, Olga O, Kelly, David, Kerr, Alastair, Clift, Dean, de Lima Alves, Flavia, Rappsilber, Juri, Marston, Adele L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910079/
https://www.ncbi.nlm.nih.gov/pubmed/24497542
http://dx.doi.org/10.7554/eLife.01374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910079/
https://www.ncbi.nlm.nih.gov/pubmed/24497542
http://dx.doi.org/10.7554/eLife.01374

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