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Comprehensive interrogation of CpG island methylation in the gene encoding COMT, a key estrogen and catecholamine regulator
BACKGROUND: The catechol-O-methyltransferase (COMT) enzyme has been widely studied due to its multiple roles in neurological functioning, estrogen biology, and methylation metabolic pathways. Numerous studies have investigated variation in the large COMT gene, with the majority focusing on single nu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910242/ https://www.ncbi.nlm.nih.gov/pubmed/24460628 http://dx.doi.org/10.1186/1755-8794-7-5 |