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Comprehensive interrogation of CpG island methylation in the gene encoding COMT, a key estrogen and catecholamine regulator

BACKGROUND: The catechol-O-methyltransferase (COMT) enzyme has been widely studied due to its multiple roles in neurological functioning, estrogen biology, and methylation metabolic pathways. Numerous studies have investigated variation in the large COMT gene, with the majority focusing on single nu...

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Detalles Bibliográficos
Autores principales: Swift-Scanlan, Theresa, Smith, Christopher T, Bardowell, Sabrina A, Boettiger, Charlotte A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910242/
https://www.ncbi.nlm.nih.gov/pubmed/24460628
http://dx.doi.org/10.1186/1755-8794-7-5