The role of CDK5 and GSK3B kinases in hyperphosphorylation of microtubule associated protein tau (MAPT) in Alzheimer's disease

Alzheimer's disease is the most common form of dementia. Abnormal hyperphosphorylation of Microtubule associated protein tau (MAPT) is one of the hallmarks of Alzheimer's disease and related tau pathies. CDK5 and GSK3B are the two main protein kinases that have an important role in the abn...

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Detalles Bibliográficos
Autores principales: Jayapalan, Saranya, Natarajan, Jeyakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2013
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910359/
https://www.ncbi.nlm.nih.gov/pubmed/24497730
http://dx.doi.org/10.6026/97320630091023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910359/
https://www.ncbi.nlm.nih.gov/pubmed/24497730
http://dx.doi.org/10.6026/97320630091023

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