Isocitrate Dehydrogenase-1 Mutations as Prognostic Biomarker in Glioblastoma Multiforme Patients in West Bohemia

Introduction. Glioblastoma multiforme (GBM) is the most malignant primary brain tumor in adults. Recent whole-genome studies revealed novel GBM prognostic biomarkers such as mutations in metabolic enzyme IDH—isocitrate dehydrogenases (IDH1 and IDH2). The distinctive mutation IDH1 R132H was uncovered...

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Detalles Bibliográficos
Autores principales: Polivka, J., Rohan, V., Pesta, M., Repik, T., Pitule, P., Topolcan, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910481/
https://www.ncbi.nlm.nih.gov/pubmed/24511544
http://dx.doi.org/10.1155/2014/735659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910481/
https://www.ncbi.nlm.nih.gov/pubmed/24511544
http://dx.doi.org/10.1155/2014/735659

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