Cargando…

Chlorotoxin-Fc Fusion Inhibits Release of MMP-2 from Pancreatic Cancer Cells

Chlorotoxin (CTX) is a 36-amino acid peptide derived from Leiurus quinquestriatus (scorpion) venom, which inhibits low-conductance chloride channels in colonic epithelial cells. It has been reported that CTX also binds to matrix metalloproteinase-2 (MMP-2), membrane type-1 MMP, and tissue inhibitor...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Ghlban, Samah, Kasai, Tomonari, Shigehiro, Tsukasa, Yin, Hong Xia, Sekhar, Sreeja, Ida, Mikiko, Sanchez, Anna, Mizutani, Akifumi, Kudoh, Takayuki, Murakami, Hiroshi, Seno, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910484/
https://www.ncbi.nlm.nih.gov/pubmed/24511528
http://dx.doi.org/10.1155/2014/152659