Cargando…

Chlorotoxin-Fc Fusion Inhibits Release of MMP-2 from Pancreatic Cancer Cells

Chlorotoxin (CTX) is a 36-amino acid peptide derived from Leiurus quinquestriatus (scorpion) venom, which inhibits low-conductance chloride channels in colonic epithelial cells. It has been reported that CTX also binds to matrix metalloproteinase-2 (MMP-2), membrane type-1 MMP, and tissue inhibitor...

Descripción completa

Detalles Bibliográficos
Autores principales:	El-Ghlban, Samah, Kasai, Tomonari, Shigehiro, Tsukasa, Yin, Hong Xia, Sekhar, Sreeja, Ida, Mikiko, Sanchez, Anna, Mizutani, Akifumi, Kudoh, Takayuki, Murakami, Hiroshi, Seno, Masaharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910484/ https://www.ncbi.nlm.nih.gov/pubmed/24511528 http://dx.doi.org/10.1155/2014/152659

Ejemplares similares

Chlorotoxin Fused to IgG-Fc Inhibits Glioblastoma Cell Motility via Receptor-Mediated Endocytosis
por: Kasai, Tomonari, et al.
Publicado: (2012)

Targeting Glioblastoma Cells Expressing CD44 with Liposomes Encapsulating Doxorubicin and Displaying Chlorotoxin-IgG Fc Fusion Protein
por: Mahmud, Hafizah, et al.
Publicado: (2018)

Efficient Drug Delivery of Paclitaxel Glycoside: A Novel Solubility Gradient Encapsulation into Liposomes Coupled with Immunoliposomes Preparation
por: Shigehiro, Tsukasa, et al.
Publicado: (2014)

Identification of Caveolin-1 as a Potential Causative Factor in the Generation of Trastuzumab Resistance in Breast Cancer Cells
por: Sekhar, Sreeja C, et al.
Publicado: (2013)

A Unique Procedure to Identify Cell Surface Markers Through a Spherical Self-Organizing Map Applied to DNA Microarray Analysis
por: Sugii, Yuh, et al.
Publicado: (2016)

Characterization of Cancer Stem-Like Cells Derived from Mouse Induced Pluripotent Stem Cells Transformed by Tumor-Derived Extracellular Vesicles
por: Yan, Ting, et al.
Publicado: (2014)

Practical Liposomal Formulation for Taxanes with Polyethoxylated Castor Oil and Ethanol with Complete Encapsulation Efficiency and High Loading Efficiency
por: Shigehiro, Tsukasa, et al.
Publicado: (2017)

Characterization of Gene Expression Patterns among Artificially Developed Cancer Stem Cells Using Spherical Self-Organizing Map
por: Seno, Akimasa, et al.
Publicado: (2016)

Cancer stem cells maintain a hierarchy of differentiation by creating their niche
por: Matsuda, Shuichi, et al.
Publicado: (2014)

Cytokine Expression and Macrophage Localization in Xenograft and Allograft Tumor Models Stimulated with Lipopolysaccharide
por: Masuda, Junko, et al.
Publicado: (2018)

A Model of Cancer Stem Cells Derived from Mouse Induced Pluripotent Stem Cells
por: Chen, Ling, et al.
Publicado: (2012)

Cancer Stem Cells Converted from Pluripotent Stem Cells and the Cancerous Niche
por: Kasai, T, et al.
Publicado: (2014)

Structure-Activity Relationship of Chlorotoxin-Like Peptides
por: Ali, Syed Abid, et al.
Publicado: (2016)

Enhanced internalization of ErbB2 in SK-BR-3 cells with multivalent forms of an artificial ligand
por: Vaidyanath, Arun, et al.
Publicado: (2011)

Neuropilin-1 drives tumor-specific uptake of chlorotoxin
por: McGonigle, Sharon, et al.
Publicado: (2019)

Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment
por: Oo, Aung Ko Ko, et al.
Publicado: (2018)

Clathrin-mediated entry and cellular localization of chlorotoxin in human glioma
por: Wiranowska, Marzenna, et al.
Publicado: (2011)

Chlorotoxin-conjugated graphene oxide for targeted delivery of an anticancer drug
por: Wang, Hao, et al.
Publicado: (2014)

Chlorotoxin-conjugated onconase as a potential anti-glioma drug
por: WANG, XIAOMIN, et al.
Publicado: (2015)

Chlorotoxin—A Multimodal Imaging Platform for Targeting Glioma Tumors
por: Cohen, Gadi, et al.
Publicado: (2018)

Chlorotoxin and Lung Cancer: A Targeting Perspective for Drug Delivery
por: Shrestha, Archana, et al.
Publicado: (2022)

Chlorotoxin binds to both matrix metalloproteinase 2 and neuropilin 1
por: Farkas, Sándor, et al.
Publicado: (2023)

Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics
por: Khanyile, Sbonelo, et al.
Publicado: (2019)

Diagnostic and Therapeutic Approaches for Glioblastoma and Neuroblastoma Cancers Using Chlorotoxin Nanoparticles
por: Boltman, Taahirah, et al.
Publicado: (2023)

Recombinant expression and downstream processing of the disulfide-rich tumor-targeting peptide chlorotoxin
por: WANG, XIAO-MIN, et al.
Publicado: (2013)

A C-Terminal Fragment of Chlorotoxin Retains Bioactivity and Inhibits Cell Migration
por: Dastpeyman, Mohadeseh, et al.
Publicado: (2019)

Chlorotoxin targets ERα/VASP signaling pathway to combat breast cancer
por: Wang, Ying, et al.
Publicado: (2019)

Chlorotoxin: A Helpful Natural Scorpion Peptide to Diagnose Glioma and Fight Tumor Invasion
por: Dardevet, Lucie, et al.
Publicado: (2015)

Anti-metastatic effect of (131)I-labeled Buthus martensii Karsch chlorotoxin in gliomas
por: Wu, Shan, et al.
Publicado: (2018)

Effects of Selective Substitution of Cysteine Residues on the Conformational Properties of Chlorotoxin Explored by Molecular Dynamics Simulations
por: Gregory, Andrew J., et al.
Publicado: (2019)

Molecular Characterization and Biodiversity of a Putative Chlorotoxin from the Iranian Yellow Scorpion Odontobuthus doriae
por: Soorki, Maryam Naderi, et al.
Publicado: (2017)

The synergistic effect of chlorotoxin-mApoE in boosting drug-loaded liposomes across the BBB
por: Formicola, Beatrice, et al.
Publicado: (2019)

Identification of two novel Chlorotoxin derivatives CA4 and CTX-23 with chemotherapeutic and anti-angiogenic potential
por: Xu, Tengfei, et al.
Publicado: (2016)

Chlorotoxin peptide-functionalized polyethylenimine-entrapped gold nanoparticles for glioma SPECT/CT imaging and radionuclide therapy
por: Zhao, Lingzhou, et al.
Publicado: (2019)

Metastasis of Cancer Stem Cells Developed in the Microenvironment of Hepatocellular Carcinoma
por: Afify, Said M., et al.
Publicado: (2019)

Erratum: Identification of two novel Chlorotoxin derivatives CA4 and CTX-23 with chemotherapeutic and anti-angiogenic potential
por: Xu, Tengfei, et al.
Publicado: (2016)

Corrigendum: Identification of two novel Chlorotoxin derivatives CA4 and CTX-23 with chemotherapeutic and anti-angiogenic potential
por: Xu, Tengfei, et al.
Publicado: (2016)

The Mediterranean scorpion Mesobuthus gibbosus (Scorpiones, Buthidae): transcriptome analysis and organization of the genome encoding chlorotoxin-like peptides
por: Diego-García, Elia, et al.
Publicado: (2014)

Radiosynthesis and Preliminary Biological Evaluation of (18)F-Fluoropropionyl-Chlorotoxin as a Potential PET Tracer for Glioma Imaging
por: Zhao, Jing, et al.
Publicado: (2018)

Daunorubicin can eliminate iPS-derived cancer stem cells via ICAD/CAD-independent DNA fragmentation
por: Seno, Akimasa, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_bf7o0lfr74q6nabp2m3773goob