Population Pharmacokinetic and Pharmacogenetic Analysis of Nevirapine in Hypersensitive and Tolerant HIV-Infected Patients from Malawi

We modeled nevirapine (NVP) pharmacokinetics in HIV-infected Malawian patients to assess the relationship between drug exposure and patient characteristics, genetic polymorphisms, and development of hypersensitivity reaction (HSR). One thousand one hundred seventeen patients were prospectively recru...

Descripción completa

Detalles Bibliográficos
Autores principales: Dickinson, Laura, Chaponda, Masautso, Carr, Daniel F., van Oosterhout, Joep J., Kumwenda, Johnstone, Lalloo, David G., Pirmohamed, Munir, Heyderman, Robert S., Khoo, Saye H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910846/
https://www.ncbi.nlm.nih.gov/pubmed/24217698
http://dx.doi.org/10.1128/AAC.02069-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910846/
https://www.ncbi.nlm.nih.gov/pubmed/24217698
http://dx.doi.org/10.1128/AAC.02069-13

Ejemplares similares