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Population Pharmacokinetic and Pharmacogenetic Analysis of Nevirapine in Hypersensitive and Tolerant HIV-Infected Patients from Malawi

We modeled nevirapine (NVP) pharmacokinetics in HIV-infected Malawian patients to assess the relationship between drug exposure and patient characteristics, genetic polymorphisms, and development of hypersensitivity reaction (HSR). One thousand one hundred seventeen patients were prospectively recru...

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Detalles Bibliográficos
Autores principales:	Dickinson, Laura, Chaponda, Masautso, Carr, Daniel F., van Oosterhout, Joep J., Kumwenda, Johnstone, Lalloo, David G., Pirmohamed, Munir, Heyderman, Robert S., Khoo, Saye H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2014
Materias:	Antiviral Agents
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910846/ https://www.ncbi.nlm.nih.gov/pubmed/24217698 http://dx.doi.org/10.1128/AAC.02069-13

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