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Immunosuppression Facilitates the Reactivation of Latent Papillomavirus Infections
At mucosal sites, papillomavirus genomes can persist in the epithelial basal layer following immune-mediated regression. Subsequent T-cell depletion stimulates a 3- to 5-log increase in the viral copy number, to levels associated with productive infection. Reappearance of microlesions was rare withi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911712/ https://www.ncbi.nlm.nih.gov/pubmed/24173230 http://dx.doi.org/10.1128/JVI.02589-13 |