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Immunosuppression Facilitates the Reactivation of Latent Papillomavirus Infections

At mucosal sites, papillomavirus genomes can persist in the epithelial basal layer following immune-mediated regression. Subsequent T-cell depletion stimulates a 3- to 5-log increase in the viral copy number, to levels associated with productive infection. Reappearance of microlesions was rare withi...

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Detalles Bibliográficos
Autores principales:	Maglennon, G. A., McIntosh, P. B., Doorbar, J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2014
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911712/ https://www.ncbi.nlm.nih.gov/pubmed/24173230 http://dx.doi.org/10.1128/JVI.02589-13

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