Inhibition of Reverse-Mode Sodium-Calcium Exchanger Activity and Apoptosis by Levosimendan in Human Cardiomyocyte Progenitor Cell-Derived Cardiomyocytes after Anoxia and Reoxygenation

Levosimendan, a known calcium sensitizer with positive inotropic and vasodilating properties, might also be cardioprotective during ischemia-reperfusion (I/R) insult. Its effects on calcium homeostasis and apoptosis in I/R injury remain unclear. Na(+)/Ca(2+) exchanger (NCX) is a critical mediator of...

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Detalles Bibliográficos
Autores principales: Li, Ping-Chun, Yang, Ya-Chi, Hwang, Guang-Yuh, Kao, Lung-Sen, Lin, Ching-Yuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911900/
https://www.ncbi.nlm.nih.gov/pubmed/24498266
http://dx.doi.org/10.1371/journal.pone.0085909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911900/
https://www.ncbi.nlm.nih.gov/pubmed/24498266
http://dx.doi.org/10.1371/journal.pone.0085909

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