Proteomics Analysis of Co-Purifying Cellular Proteins Associated with rAAV Vectors

Recombinant adeno-associated vectors (rAAV) are commonly purified by either chromatography or equilibrium CsCl gradient. Nevertheless, even after purification various cellular proteins often associate with rAAV vector capsids. Such co-purifying cellular proteins may raise concern about safety of gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Biao, Duan, Xunbao, Chow, Hoi Yee, Chen, Lingxia, Lu, Hui, Wu, Wenman, Hauck, Bernd, Wright, Fraser, Kapranov, Philipp, Xiao, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911921/
https://www.ncbi.nlm.nih.gov/pubmed/24498275
http://dx.doi.org/10.1371/journal.pone.0086453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911921/
https://www.ncbi.nlm.nih.gov/pubmed/24498275
http://dx.doi.org/10.1371/journal.pone.0086453

Ejemplares similares