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Proteomics Analysis of Co-Purifying Cellular Proteins Associated with rAAV Vectors
Recombinant adeno-associated vectors (rAAV) are commonly purified by either chromatography or equilibrium CsCl gradient. Nevertheless, even after purification various cellular proteins often associate with rAAV vector capsids. Such co-purifying cellular proteins may raise concern about safety of gen...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911921/ https://www.ncbi.nlm.nih.gov/pubmed/24498275 http://dx.doi.org/10.1371/journal.pone.0086453 |