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Novel Insights into the Cardio-Protective Effects of FGF21 in Lean and Obese Rat Hearts

AIMS: Fibroblast growth factor 21 (FGF21) is a hepatic metabolic regulator with pleotropic actions. Its plasma concentrations are increased in obesity and diabetes; states associated with an increased incidence of cardiovascular disease. We therefore investigated the direct effect of FGF21 on cardio...

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Detalles Bibliográficos
Autores principales: Patel, Vanlata, Adya, Raghu, Chen, Jing, Ramanjaneya, Manjunath, Bari, Muhammad F., Bhudia, Sunil K., Hillhouse, Edward W., Tan, Bee K., Randeva, Harpal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911936/
https://www.ncbi.nlm.nih.gov/pubmed/24498293
http://dx.doi.org/10.1371/journal.pone.0087102