A Recombinant Rabies Virus Encoding Two Copies of the Glycoprotein Gene Confers Protection in Dogs against a Virulent Challenge

The rabies virus (RABV) glycoprotein (G) is the principal antigen responsible for the induction of virus neutralizing antibodies (VNA) and is the major modality of protective immunity in animals. A recombinant RABV HEP-Flury strain was generated by reverse genetics to encode two copies of the G-gene...

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Detalles Bibliográficos
Autores principales: Liu, Xiaohui, Yang, Youtian, Sun, Zhaojin, Chen, Jing, Ai, Jun, Dun, Can, Fu, Zhen F., Niu, Xuefeng, Guo, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911940/
https://www.ncbi.nlm.nih.gov/pubmed/24498294
http://dx.doi.org/10.1371/journal.pone.0087105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911940/
https://www.ncbi.nlm.nih.gov/pubmed/24498294
http://dx.doi.org/10.1371/journal.pone.0087105

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