Temporal Dynamics of Glyoxalase 1 in Secondary Neuronal Injury

BACKGROUND: Enhanced glycolysis leads to elevated levels of the toxic metabolite methylglyoxal which contributes to loss of protein-function, metabolic imbalance and cell death. Neurons were shown being highly susceptible to methylglyoxal toxicity. Glyoxalase 1 as an ubiquitous enzyme reflects the m...

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Detalles Bibliográficos
Autores principales: Pieroh, Philipp, Koch, Marco, Wagner, Daniel-Christoph, Boltze, Johannes, Ehrlich, Angela, Ghadban, Chalid, Hobusch, Constance, Birkenmeier, Gerd, Dehghani, Faramarz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911945/
https://www.ncbi.nlm.nih.gov/pubmed/24498315
http://dx.doi.org/10.1371/journal.pone.0087364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911945/
https://www.ncbi.nlm.nih.gov/pubmed/24498315
http://dx.doi.org/10.1371/journal.pone.0087364

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