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Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma

Malignant cells constitutively express Natural killer group 2, member D (NKG2D) or DNAX Accessory Molecule-1 (DNAM-1) ligands, yet they are often unable to trigger a robust cytotoxic cell response. It may be therapeutically useful to implement strategies aimed at increasing the density of NKG2D and...

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Detalles Bibliográficos
Autores principales: Soriani, Alessandra, Fionda, Cinzia, Ricci, Biancamaria, Iannitto, Maria Luisa, Cippitelli, Marco, Santoni, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912005/
https://www.ncbi.nlm.nih.gov/pubmed/24498552
http://dx.doi.org/10.4161/onci.26663