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Synthetic Multivalent Antifungal Peptides Effective against Fungi

Taking advantage of the cluster effect observed in multivalent peptides, this work describes antifungal activity and possible mechanism of action of tetravalent peptide (B4010) which carries 4 copies of the sequence RGRKVVRR through a branched lysine core. B4010 displayed better antifungal propertie...

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Detalles Bibliográficos
Autores principales: Lakshminarayanan, Rajamani, Liu, Shouping, Li, Jianguo, Nandhakumar, Muruganantham, Aung, Thet Tun, Goh, Eunice, Chang, Jamie Ya Ting, Saraswathi, Padhmanaban, Tang, Charles, Safie, Siti Radiah Binte, Lin, Lim Yih, Riezman, Howard, Lei, Zhou, Verma, Chandra S., Beuerman, Roger W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912015/
https://www.ncbi.nlm.nih.gov/pubmed/24498363
http://dx.doi.org/10.1371/journal.pone.0087730