Enhancement of immunogenicity and efficacy of a plasmid DNA rabies vaccine by nanoformulation with a fourth-generation amine-terminated poly(ether imine) dendrimer

PURPOSE: Delayed onset of, and low magnitude of, protective immune responses are major drawbacks limiting the practical utility of plasmid vaccination against rabies. In this study we evaluated whether nanoformulation with the novel poly(ether imine) (PETIM) dendrimer can enhance the immunogenicity...

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Detalles Bibliográficos
Autores principales: Ullas, Padinjaremattathil Thankappan, Madhusudana, Shampur Narayan, Desai, Anita, Sagar, Bhadravathi Kenchappa Chandrasekhar, Jayamurugan, Govindasamy, Rajesh, Yamajala Bhaskara Rama Durga, Jayaraman, Narayanaswami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912024/
https://www.ncbi.nlm.nih.gov/pubmed/24501540
http://dx.doi.org/10.2147/IJN.S53415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912024/
https://www.ncbi.nlm.nih.gov/pubmed/24501540
http://dx.doi.org/10.2147/IJN.S53415

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