Disruption of Myelin Leads to Ectopic Expression of K(V)1.1 Channels with Abnormal Conductivity of Optic Nerve Axons in a Cuprizone-Induced Model of Demyelination

The molecular determinants of abnormal propagation of action potentials along axons and ectopic conductance in demyelinating diseases of the central nervous system, like multiple sclerosis (MS), are poorly defined. Widespread interruption of myelin occurs in several mouse models of demyelination, re...

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Detalles Bibliográficos
Autores principales: Bagchi, Bandita, Al-Sabi, Ahmed, Kaza, Seshu, Scholz, Dimitri, O'Leary, Valerie B., Dolly, J. Oliver, Ovsepian, Saak V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912067/
https://www.ncbi.nlm.nih.gov/pubmed/24498366
http://dx.doi.org/10.1371/journal.pone.0087736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912067/
https://www.ncbi.nlm.nih.gov/pubmed/24498366
http://dx.doi.org/10.1371/journal.pone.0087736

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