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Loss of WISP2/CCN5 in Estrogen-Dependent MCF7 Human Breast Cancer Cells Promotes a Stem-Like Cell Phenotype

It has been proposed that the epithelial-mesenchymal transition (EMT) in mammary epithelial cells and breast cancer cells generates stem cell features. WISP2 (Wnt-1-induced signaling protein-2) plays an important role in maintenance of the differentiated phenotype of estrogen receptor-positive breas...

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Detalles Bibliográficos
Autores principales: Ferrand, Nathalie, Gnanapragasam, Anne, Dorothee, Guillaume, Redeuilh, Gérard, Larsen, Annette K., Sabbah, Michèle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912128/
https://www.ncbi.nlm.nih.gov/pubmed/24498388
http://dx.doi.org/10.1371/journal.pone.0087878