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Anti-Cancer Effects of REIC/Dkk-3-encoding Adenoviral Vector for the Treatment of Non-small Cell Lung Cancer

OBJECTIVES: REIC/Dkk-3 is down-regulated in a broad range of human cancer cells and is considered to function as a tumor suppressor. We previously reported that REIC/Dkk-3-expressing adenovirus vector (Ad-REIC) induced endoplasmic reticulum (ER) stress and cancer-specific apoptosis in human prostate...

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Detalles Bibliográficos
Autores principales: Shien, Kazuhiko, Tanaka, Norimitsu, Watanabe, Masami, Soh, Junichi, Sakaguchi, Masakiyo, Matsuo, Keitaro, Yamamoto, Hiromasa, Furukawa, Masashi, Asano, Hiroaki, Tsukuda, Kazunori, Nasu, Yasutomo, Huh, Nam-Ho, Miyoshi, Shinichiro, Kumon, Hiromi, Toyooka, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912155/
https://www.ncbi.nlm.nih.gov/pubmed/24498395
http://dx.doi.org/10.1371/journal.pone.0087900