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Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD Risk Locus 19q13.2
Genome-wide association studies (GWAS) and candidate gene studies have identified a number of risk loci associated with the smoking-related disease COPD, a disorder that originates in the airway epithelium. Since airway basal cell (BC) stem/progenitor cells exhibit the earliest abnormalities associa...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912203/ https://www.ncbi.nlm.nih.gov/pubmed/24498427 http://dx.doi.org/10.1371/journal.pone.0088051 |