Microtubules Accelerate the Kinase Activity of Aurora-B by a Reduction in Dimensionality

Aurora-B is the kinase subunit of the Chromosome Passenger Complex (CPC), a key regulator of mitotic progression that corrects improper kinetochore attachments and establishes the spindle midzone. Recent work has demonstrated that the CPC is a microtubule-associated protein complex and that microtub...

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Detalles Bibliográficos
Autores principales: Noujaim, Michael, Bechstedt, Susanne, Wieczorek, Michal, Brouhard, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912212/
https://www.ncbi.nlm.nih.gov/pubmed/24498282
http://dx.doi.org/10.1371/journal.pone.0086786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912212/
https://www.ncbi.nlm.nih.gov/pubmed/24498282
http://dx.doi.org/10.1371/journal.pone.0086786

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