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Microtubules Accelerate the Kinase Activity of Aurora-B by a Reduction in Dimensionality
Aurora-B is the kinase subunit of the Chromosome Passenger Complex (CPC), a key regulator of mitotic progression that corrects improper kinetochore attachments and establishes the spindle midzone. Recent work has demonstrated that the CPC is a microtubule-associated protein complex and that microtub...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912212/ https://www.ncbi.nlm.nih.gov/pubmed/24498282 http://dx.doi.org/10.1371/journal.pone.0086786 |