CLIC4 regulates TGF-β dependent myofibroblast differentiation to produce a cancer stroma

Cancer stroma has a profound influence on tumor development and progression. The conversion of fibroblasts to activated myofibroblasts is a hallmark of reactive tumor stroma. Among a number of factors involved in this conversion, TGF-β has emerged as a major regulator. CLIC4, an integral protein in...

Descripción completa

Detalles Bibliográficos
Autores principales: Shukla, A, Edwards, R, Yang, Y, Hahn, A, Folkers, K, Ding, J, Padmakumar, VC, Cataisson, C, Suh, KS, Yuspa, SH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912213/
https://www.ncbi.nlm.nih.gov/pubmed/23416981
http://dx.doi.org/10.1038/onc.2013.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912213/
https://www.ncbi.nlm.nih.gov/pubmed/23416981
http://dx.doi.org/10.1038/onc.2013.18

Ejemplares similares