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CLIC4 regulates TGF-β dependent myofibroblast differentiation to produce a cancer stroma
Cancer stroma has a profound influence on tumor development and progression. The conversion of fibroblasts to activated myofibroblasts is a hallmark of reactive tumor stroma. Among a number of factors involved in this conversion, TGF-β has emerged as a major regulator. CLIC4, an integral protein in...
Autores principales: | Shukla, A, Edwards, R, Yang, Y, Hahn, A, Folkers, K, Ding, J, Padmakumar, VC, Cataisson, C, Suh, KS, Yuspa, SH |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912213/ https://www.ncbi.nlm.nih.gov/pubmed/23416981 http://dx.doi.org/10.1038/onc.2013.18 |
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