15-PGDH inhibits hepatocellular carcinoma growth through 15-keto-PGE(2)/PPARγ-mediated activation of p21(WAF1/Cip1)

15-hydroxyprostaglandin dehydrogenase (15-PGDH) is a key enzyme in prostaglandin metabolism. This study provides important evidence for inhibition of hepatocellular carcinoma (HCC) growth by 15-PGDH through the 15-keto-PGE(2)/PPARγ/p21(WAF1/Cip1) signaling pathway. Forced overexpression of 15-PGDH i...

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Detalles Bibliográficos
Autores principales: Lu, Dongdong, Han, Chang, Wu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912217/
https://www.ncbi.nlm.nih.gov/pubmed/23542179
http://dx.doi.org/10.1038/onc.2013.69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912217/
https://www.ncbi.nlm.nih.gov/pubmed/23542179
http://dx.doi.org/10.1038/onc.2013.69

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