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15-PGDH inhibits hepatocellular carcinoma growth through 15-keto-PGE(2)/PPARγ-mediated activation of p21(WAF1/Cip1)

15-hydroxyprostaglandin dehydrogenase (15-PGDH) is a key enzyme in prostaglandin metabolism. This study provides important evidence for inhibition of hepatocellular carcinoma (HCC) growth by 15-PGDH through the 15-keto-PGE(2)/PPARγ/p21(WAF1/Cip1) signaling pathway. Forced overexpression of 15-PGDH i...

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Detalles Bibliográficos
Autores principales:	Lu, Dongdong, Han, Chang, Wu, Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912217/ https://www.ncbi.nlm.nih.gov/pubmed/23542179 http://dx.doi.org/10.1038/onc.2013.69

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