A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy

Killing cancer cells through the induction of apoptosis is one of the main mechanisms of chemotherapy. However, numerous cancer cells have primary or acquired apoptosis resistance, resulting in chemoresistance. In this study, using a novel chalcone derivative chalcone-24 (Chal-24), we identified a n...

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Detalles Bibliográficos
Autores principales: He, Weiyang, Wang, Qiong, Srinivasan, Balasubramanian, Xu, Jennings, Padilla, Mabel T., Li, Zi, Wang, Xia, Liu, Yushi, Gou, Xin, Shen, Han-Ming, Xing, Chengguo, Lin, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912228/
https://www.ncbi.nlm.nih.gov/pubmed/23831571
http://dx.doi.org/10.1038/onc.2013.256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912228/
https://www.ncbi.nlm.nih.gov/pubmed/23831571
http://dx.doi.org/10.1038/onc.2013.256

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