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A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy
Killing cancer cells through the induction of apoptosis is one of the main mechanisms of chemotherapy. However, numerous cancer cells have primary or acquired apoptosis resistance, resulting in chemoresistance. In this study, using a novel chalcone derivative chalcone-24 (Chal-24), we identified a n...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912228/ https://www.ncbi.nlm.nih.gov/pubmed/23831571 http://dx.doi.org/10.1038/onc.2013.256 |