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Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides

Dupuytren's disease (DD) is a benign fibroproliferative disease of the hand. It is characterized by the excessive production of extracellular matrix (ECM) proteins, which form a strong fibrous tissue between the handpalm and fingers, permanently disrupting the fine movement ability. The major c...

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Detalles Bibliográficos
Autores principales: Karkampouna, Sofia, Kruithof, Boudewijn PT, Kloen, Peter, Obdeijn, Miryam C, van der Laan, Annelies MA, Tanke, Hans J, Kemaladewi, Dwi U, Hoogaars, Willem MH, ‘t Hoen, Peter AC, Aartsma-Rus, Annemieke, Clark, Ian M, ten Dijke, Peter, Goumans, Marie-José, Kruithof-de Julio, Marianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912325/
https://www.ncbi.nlm.nih.gov/pubmed/24448195
http://dx.doi.org/10.1038/mtna.2013.69